Since laboratory filtration is a common and critical step across clinical and research laboratories, make it simple, fast, and efficient with our range of high-quality filtration devices.

From high-performance, application specific filters to economic syringe filters and specialized equipment for automated systems, mobile phase filtration, and difficult to filter samples, Cytiva offers a broad range of filtration devices designed to suit your workflow.

Syringe filters

What are syringe filters?

Syringe filters are a type filtration device composed of a membrane and a plastic housing designed to fit on the outlet of a syringe. These devices are used to remove particulates from low-volume, liquid samples.

Are syringe filters re-usable?

Whatman™ syringe filters are single-use for convenience, speed, and performance. It is not recommended to re-use syringe filters due to the risk of cross-contamination, which can compromise your results.

How do I choose a syringe filter?

There are two characteristics of a syringe filter to consider when selecting one appropriate for your application: the size and the membrane. Syringe filter size is determined by the volume of your sample. If you have high sample volumes, it is generally recommended to select a syringe filter with a large membrane area.

The choice in membrane type will depend on your application. For example, if you are filtering an organic solvent you may want to consider an inorganic Anopore membrane such as those found in WhatmanTM Anotop Syringe Filters. To find out more about how to select the right membrane for your application, take a look at our Membrane Selection Guide.

What is the best method of using a syringe filter?

Whatman™ syringe filters are simple and easy to use filtration devices. First, draw your sample into the syringe and secure the filter onto the tip of the syringe. Hold the syringe with the filter pointing upwards and “top off” by pushing a few drops through the filter. Position the filter tip over the sample receptacle and apply gentle, steady positive pressure to push the sample through the syringe filter.

Difficult to filter samples

What types of samples might be difficult to filter?

Samples with high quantities of particulates, such as wastewater and sludge, are generally difficult to filter as they can quickly clog filter membranes. Highly viscous samples, such as honey, can also be difficult to filter since they generate backpressure and substantially slow down filtration.

What filtration devices are available for difficult to filter samples?

For high particulate load samples, choosing filtration devices that house two or more filter layers, such as the Whatman™ GD/X syringe filters, can aid efficient filtration without blockage. The first filter acts to remove larger particles, while subsequent filters remove finer particles, allowing for much greater sample throughput.

All-in-one filters and filter vials

What are the benefits of all-in-one filtration devices?

Since all-in-one filters are integrated devices that include the collection receptacle, you can save time, reduce waste, and reduce the number of sample handling steps. For example, compared to a syringe filter, the Whatman™ Autovial Syringeless Filters reduce the number of sample handling steps from six to three.

Filters for automated systems

What are the benefits of automated filtration?

As with all laboratory automation, automated filtration can save you time and minimizes sample handling steps. Whatman™ Roby syringe filters can be ordered with a range of different membrane types, so you’ll be sure to find the right filter to automate your workflow.

Mobile phase filtration

What is mobile phase filtration?

Mobile phase filtration refers to the removal of particulate matter from the mobile phase (solvent) during HPLC preparation. It is an important process intended to prevent premature column choking, extend the life of HPLC consumables, and limit wear and tear leading to reduction in maintenance costs and increased machine uptime. Mobile phase filtration systems also helps in solvent degassing, which can otherwise lead to spurious peaks.

To help you identify the most appropriate filtration device for your application, try our filter selector, or contact our specialists to discuss your needs.