Robust and scalable AAV production
Read about the upstream process development and optimization of AAV production in batch and perfusion modes.
Adherent cell process
Read about the scalable upstream process we developed for rAAV8 in HEK293 cells.
Suspension cell process
Learn how we developed a scalable, cGMP compatible process in a stirred-tank, single-use bioreactor.
Effective AAV polishing
See how we achieved baseline separation of full and empty capsids with ~ 80% VG recovery and purity.
iCELLis™ fixed-bed bioreactors
Technology for adherent cells used in several approved gene therapies.
ÄKTA ready™ 450 single-use system
Purify small quantities efficiently in a GMP environment.
Capto™ Q resin
Dextran surface extenders on this chromatography resin enhance separation of full and empty capsids.
Capto™ AVB affinity resin
Efficient, industrial-scale purification of AAV of several subclasses by affinity chromatography.